The outcome of infection with SARS-CoV-2, the virus that causes Covid-19, is determined by a person’s immune response. That outcome may be good, when the immune system halts the virus with barely an obvious symptom; bad, when the immune response causes symptoms of disease; or ugly, when an over-cooked response triggers severe or life-threatening reaction.During this event, two leading immunologists will describe how our immune defenses recognize and respond to viral threats, tease out the roles that the different components of the immune system play in protection and damage, and discuss the characteristics of vaccines that could generate protective immunity to SARS-CoV-2 in a large fraction of the population.Join Knowable Magazine for a live conversation – and get your questions answered. Please submit questions prior to the event either by clicking on "Ask a Question" or by emailing them to events@knowablemagazine.org.SpeakersAkiko Iwasaki, Professor of Immunobiology and Molecular, Cellular and Developmental Biology, Yale School of Medicine. She tweets as @VirusesImmunity.E. John Wherry, Director, Institute for Immunology, University of Pennsylvania. He tweets as @EJohnWherry.ModeratorRichard Gallagher, President and Editor-in-Chief, Annual Reviews. He tweets as @RichardG_AR.

This event is part of Reset, an ongoing series of live events and science journalism exploring how the world is navigating the coronavirus pandemic, its consequences, and the way forward. Keep an eye out for future Reset events coming this winter. Dates, times, and speakers to be announced on Knowable Magazine.

Reset is supported by a grant from the Alfred P. Sloan Foundation. Knowable Magazine is a product of Annual Reviews, a nonprofit publisher dedicated to synthesizing and integrating knowledge for the progress of science and the benefit of society.

Covid-19 and the Immune System: The Good, the Bad, and the Ugly